Funds from this grant will help Greg Caporaso develop an interactive educational text, An Introduction to Applied Bioinformatics (IAB), that will introduce readers to the core concepts and algorithms of bioinformatics. Focusing on applications to real-world problems, the project will produce a set of interactive notebooks that will allow students to learn about the complex computational methods used in modern bioinformatics in an engaging, hands-on fashion using live code that can be altered, tweaked, executed, and adapted to their own research or data. The project represents an innovative experiment in how advances in information technology are opening new frontiers for high-quality education on computational methods.