This grant provides support for the Build-A-Cell research coordination network, a collaborative, international community of more than 100 scientists drawn from about 100 labs across the globe whose work focuses on building synthetic cells. The Build-A-Cell network will use Sloan grant funding to run two in-person workshops each year and to support ongoing working groups that collaborate between workshops. The workshops are designed as hands-on working meetings that bring participants together to exchange methods, compare results, identify shared technical challenges, and coordinate community-led projects. The working groups will pursue targeted objectives across areas such as modeling, integration of cell components, education and outreach, biosafety and security, international engagement and policy, and biomanufacturing. Sloan funds will be used to support the logistics needed to sustain these activities, including travel support for workshop participation and partial support for a coordinator who will organize meetings and help keep working groups moving.